I Started Taking Paxil Again and Cant Stop Shaking

Brand names:

Paxil®
- Tablets (immediate release): x mg, 20 mg, 30 mg, 40 mg
- Liquid break: 10 mg/5 mL
Paxil CR®
- Tablets (controlled release): 12.v mg, 25 mg, 37.5 mg
Pexeva®
- Tablets (firsthand release): 10 mg, 20 mg, 30 mg, xl mg
Brisdelle®
- Capsule: 7.5 mg

Generic name: paroxetine (pa ROKS due east teen)

All FDA black box warnings are at the stop of this fact sheet. Please review before taking this medication.

What is Paroxetine And What Does It Care for?

Paroxetine is an antidepressant medication that works in the brain. It is approved for the handling of major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder (social phobia), panic disorder, obsessive compulsive disorder (OCD), posttraumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD), and for vasomotor symptoms (hot flashes, night sweats, flushes, etc.) associated with menopause (Brisdelle®).

Symptoms of depression include:

Depressed mood - feeling sorry, empty, or bawling
Feeling worthless, guilty, hopeless, and helpless
Loss of interest or pleasance in your usual activities
Sleep and eat more than or less than usual (for about people it is less)
Low energy, trouble concentrating, or thoughts of death (suicidal thinking)
Psychomotor agitation ('nervous free energy')
Psychomotor retardation (feeling like you are moving and thinking in tedious motion)
Suicidal thoughts or behaviors

Generalized Anxiety Disorder (GAD) occurs when a person experiences excessive anxiety or worry for at least six months. Other symptoms include:

Restlessness
Fatigue (low energy, feeling tired all the time)
Difficulty concentrating
Irritability
Musculus tension
Sleep disturbance (difficulty falling comatose or waking upwardly in the middle of the night)

Obsessive Compulsive Disorder (OCD) occurs when a person experiences the post-obit symptoms at the aforementioned time:

Obsessions (unwanted, recurrent, and agonizing thoughts)
Compulsions (repetitive, ritualized behaviors that the person feels driven to perform in order to lessen the anxiety produced by the obsession)

Panic Disorder occurs when a person experiences unexpected and repeated episodes of intense fearfulness. These episodes have physical symptoms including chest pain, shortness of breath, heart palpitations, sweating, dizziness, and nausea. Fright of future episodes is also part of panic disorder.

PTSD occurs when a person experiences a traumatic event (east.g., assault, combat experience) so later feels on edge; avoids situations that remind them of the effect; and experiences flashbacks or nightmares.

Premenstrual dysphoric disorder (PMDD) is a condition where a woman experiences depression, tension, and irritability for a few days prior to menstruation that end when catamenia begins. These symptoms are more severe than those of premenstrual syndrome (PMS).

Social phobia/social feet disorder is a fear of situations where ane may experience as if they are being judged by others. Symptoms include:

Blushing
Difficulty talking
Nausea
Sweating
Shaking

Paroxetine may likewise be helpful when prescribed "off-label" for irritable bowel syndrome and obsessive-compulsive disorder in children. "Off-label" means that it hasn't been approved by the Food and Drug Administration for this condition. Your mental health provider should justify his or her thinking in recommending whatever "off-label" treatment. They should be clear about the limits of the inquiry around that medication and if in that location are any other options.

What Is The Most Of import Information I Should Know About Paroxetine?

Do not stop taking paroxetine, even when you experience better. With input from you, your wellness care provider will appraise how long y'all will need to take the medicine.

Missing doses of paroxetine may increase your risk for relapse in your symptoms.

Stopping paroxetine abruptly may issue in one or more of the following withdrawal symptoms: irritability, nausea, feeling dizzy, vomiting, nightmares, headache, and/or paresthesias (prickling, tingling sensation on the skin).

Low is besides a role of bipolar affliction. People with bipolar disorder who take antidepressants may be at run a risk for "switching" from depression into mania. Symptoms of mania include "loftier" or irritable mood, very high self-esteem, decreased need for sleep, pressure to keep talking, racing thoughts, being easily distracted, frequently involved in activities with a large adventure for bad consequences (for example, excessive buying sprees).

Medical attention should be sought if serotonin syndrome is suspected. Please refer to serious side furnishings for signs/symptoms.

Are There Specific Concerns Almost Paroxetine And Pregnancy?

If yous are planning on becoming meaning, notify your health intendance provider to best manage your medications. People living with MDD who wish to become significant face important decisions. Untreated MDD has risks to the fetus, likewise equally the mother. It is important to discuss the risks and benefits of treatment with your doctor and caregivers. Exposure of paroxetine to the fetus during the start trimester of pregnancy tin increase the gamble of cardiovascular malformations. For women who take antidepressant medications during weeks 13 through the end of their pregnancy (second and third trimesters), there is a risk that the baby can be built-in before information technology is fully developed (before 37 weeks).

For mothers who have taken SSRIs during their pregnancy, there appears to be less than a 1% risk of infants developing persistent pulmonary hypertension. This is a potentially fatal status that is associated with employ of the antidepressant in the second half of pregnancy. Even so, women who discontinued antidepressant therapy were 5 times more likely to take a depression relapse than those who continued their antidepressant. If y'all are meaning, please discuss the risks and benefits of antidepressant use with your health care provider.

Caution is advised with breastfeeding since paroxetine does pass into breast milk.

What Should I Hash out With My Health Care Provider Before Taking Paroxetine?

Symptoms of your condition that carp y'all the virtually
If you have thoughts of suicide or harming yourself
Medications you have taken in the past for your condition, whether they were effective or acquired any adverse effects
If you experience side effects from your medications, discuss them with your provider. Some side effects may pass with time, simply others may crave changes in the medication.
Any other psychiatric or medical problems you take, including a history of bipolar disorder, bone problems, liver or kidney bug, bleeding or center problems, glaucoma, depression sodium in your blood or seizure disorder.
All other medications yous are currently taking (including over the counter products, herbal and nutritional supplements) and any medication allergies you lot take
Other not-medication treatment you are receiving, such as talk therapy or substance abuse treatment. Your provider can explain how these unlike treatments work with the medication.
If you are significant, plan to get significant, or are breastfeeding
If you drink booze or use drugs

How Should I Take Paroxetine?

Paroxetine is commonly taken one time per mean solar day with or without food.

Typically patients begin at a low dose of medicine and the dose is increased slowly over several weeks.

The dose usually ranges from 10 mg to twoscore mg (75 mg for controlled release). Only your health intendance provider tin determine the correct dose for you.

If you are taking paroxetine for PMDD, it can be taken once daily (everyday) or intermittently (usually starting 14 days prior to period through the starting time full day of period of each bicycle). Discuss this with your prescriber.

The liquid should be measured with a dosing spoon or oral syringe which you can get from your pharmacy.

The controlled release class as well equally Pexeva® should be swallowed whole. They should not be chewed, crushed, or broken.

Consider using a agenda, pillbox, warning clock, or cell telephone alarm to help yous call back to take your medication. You may also ask a family fellow member or friend to remind you or bank check in with yous to exist certain you are taking your medication.

What Happens If I Miss A Dose Of Paroxetine?

If you miss a dose of paroxetine, take information technology as shortly as you remember, unless information technology is closer to the fourth dimension of your next dose. Discuss this with your health care provider. Do not double your adjacent dose or take more than what is prescribed.

What Should I Avoid While Taking Paroxetine?

Avoid drinking alcohol or using illegal drugs while you are taking antidepressant medications. They may decrease the benefits (e.g., worsen your status) and increase adverse effects (e.g., sedation) of the medication.

What Happens If I Overdose With Paroxetine?

If an overdose occurs, call your doctor or 911. Yous may need urgent medical intendance. Yous may too contact the poisonous substance control heart at 1-800-222-1222.

A specific treatment to reverse the effects of paroxetine does not be.

What Are The Possible Side Effects Of Paroxetine?

Common side effects

Headache, nausea, constipation, diarrhea, dry mouth, increased sweating, and dizziness
Feeling nervous, restless, fatigued, sleepy or having problem sleeping (insomnia)

These will frequently improve over the kickoff calendar week or two as you proceed to take the medication.

Sexual side effects, such as problems with orgasm or ejaculatory delay often do non diminish over time.

Rare/serious side effects

Low sodium blood levels (symptoms of low sodium levels may include headache, weakness, difficulty concentrating and remembering), teeth grinding, angle closure glaucoma (symptoms of bending closure glaucoma may include eye hurting, changes in vision, swelling or redness in or around eye)

Serotonin syndrome (symptoms may include shivering, diarrhea, defoliation, astringent musculus tightness, fever, seizures, and expiry), seizure

Discontinuation syndrome (precipitous discontinuation may include nausea, sweating, dysphoric mood, irritability, agitation, dizziness, sensory disturbances as electric shock sensations, tremor, anxiety, confusion, headache, lethargy, emotional lability, insomnia, hypomania, ringing in the ears, and seizures.

SSRI antidepressants including paroxetine may increase the risk of bleeding events. Combined use of aspirin, nonsteroidal anti-inflammatory drugs (e.g., ibuprofen, naproxen), warfarin, and other anti-coagulants may increment this hazard. This may include gums that bleed more easily, nosebleed, or gastrointestinal bleeding. Some cases accept been life threatening.

Hypersensitivity to paroxetine. Telephone call your health care provider if yous get rash, hives, swelling, or difficulty animate. Avert with known hypersensitivity to paroxetine or whatsoever ingredients mixed with it.

Are There Any Risks For Taking Paroxetine For Long Periods Of Fourth dimension?

To date, at that place are no known problems associated with long term use of paroxetine. It is a safe and effective medication when used every bit directed.

What Other Medications May Interact With Paroxetine?

Paroxetine should non be taken with or within two weeks of taking monoamine oxidase inhibitors (MAOIs). These include phenelzine (Nardil®), tranycypromine (Parnate®), isocarboxazid (Marplan®), rasagiline (Azilect®), and selegiline (Emsam®).

Although rare, there is an increased chance of serotonin syndrome when paroxetine is used with other medications that increase serotonin, such every bit other antidepressants, buspirone (Buspar), lithium (Lithobid) migraine medications called "triptans" (e.chiliad., Imitrex®), some pain medications (e.grand., tramadol (Ultram®)), the antibiotic linezolid (Zyvox®), or intravenous methylene blue.

Paroxetine may increase the levels of:

Atomoxetine (Stratterra®)
Antipsychotics, such equally aripiprazole (Abilify®), risperidone (Risperdal®)
Warfarin (Coumadin®)
Cardiac medications such equally propafenone (Rythmol®), metoprolol (Toprol Twoscore®, Lopressor®) and propranolol (Inderal®)
Tricyclic antidepressants, such as, desipramine (Norpramin®), imipramine (Tofranil®)

Combining paroxetine with thioridazine (Mellaril®), tamoxifen (Soltamox), pimozide (Orap) is not recommended.

Paroxetine may increment the effects of other medications that can cause bleeding (e.g., ibuprofen (Advil®, Motrin®), warfarin (Coumadin®) and aspirin).

How Long Does It Accept For Paroxetine To Work?

Sleep, energy, or appetite may show some improvement within the outset 1-2 weeks. Comeback in these physical symptoms tin can be an important early on signal that the medication is working. Depressed mood and lack of interest in activities may demand upwards to half-dozen-8 weeks to fully improve.

Summary of FDA Blackness Box Warnings

Suicidal thoughts or actions in children and adults

Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients with major depressive disorder (MDD), both developed and pediatric, may feel worsening of their depression and/or the emergence of suicidal ideation and behavior (suicidality) or unusual changes in beliefs, whether they are taking antidepressant medications. This adventure may persist until significant remission occurs.

In brusque-term studies, antidepressants increased the risk of suicidality in children, adolescents, and young adults when compared to placebo. Curt-term studies did not show an increase in the hazard of suicidality with antidepressants compared to placebo in adults beyond age 24. Adults age 65 and older taking antidepressants accept a decreased take a chance of suicidality. Patients, their families, and caregivers should be alert to the emergence of anxiety, restlessness, irritability, aggressiveness and insomnia. If these symptoms emerge, they should be reported to the patient's prescriber or health care professional. All patients beingness treated with antidepressants for any indication should sentinel for and notify their health care provider for worsening symptoms, suicidality and unusual changes in beliefs, especially during the first few months of treatment.

Paroxetine extended release is not approved for employ in pediatric patients.

Provided by

(Dec 2020)

©2020 The College of Psychiatric and Neurologic Pharmacists (CPNP) and the National Brotherhood on Mental Illness (NAMI). CPNP and NAMI brand this document available under the Creative Eatables Attribution-No Derivatives 4.0 International License. Terminal Updated: January 2016.

This information is existence provided as a customs outreach effort of the College of Psychiatric and Neurologic Pharmacists. This information is for educational and informational purposes merely and is not medical advice. This information contains a summary of important points and is non an exhaustive review of information about the medication. Always seek the advice of a physician or other qualified medical professional person with any questions you may have regarding medications or medical conditions. Never delay seeking professional medical advice or disregard medical professional advice as a effect of whatsoever information provided herein. The College of Psychiatric and Neurologic Pharmacists disclaims whatsoever and all liability alleged as a result of the data provided herein.

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